NMImETIC NanoBone Plus

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NMImETIC NanoBone Plus is the first commercial synthetic osteoinductive product in the world in which two mineral and organic phases are in nano-scale. Its organic and mineral phase mimics the structure of natural bone. It is a product, composed of NMImETIC Peptide Nanofibers D (Peptide vial), a synthetic anti-inflammatory, angiogenic, and osteogenic self-assembling peptide nanofibers, nanoceramics (Syringe) and NMImETIC Swelling NanoBone Powder vial, acting as a scaffold. NMImETIC Swelling NanoBone Powder vial, compared to allografts of equal weight, exhibits a 17.56% increase in volume, and compared to osteon as a synthetic bone product, it shows a 38.3% volume increase. This means that for an equal weight, patients require less of this bone product. As a result, it will have lower total costs for patients while providing significant bone regeneration benefits. The part of peptide vial is US PATENT US10485895B2. The product is free from surfactants and toxic agents, and since it is entirely synthetic, there is no risk of contamination from a biological source. When NMImETIC NanoBone Plus interacts with bone, it creates a three-dimensional scaffold that fills cracks and repairs defects. Upon contact with bone, it activates the bone surface, leading to exposure of bone biomolecules on the bone surface, stimulating angiogenesis and strong bone regeneration. It significantly reduces the toothless time of dental implant patients compared to Allograft and Xenograft products.

NMImETIC NanoBone Plus

Name: NMImETIC NanoBone Plus
SKU: 10927
Availability: InStock

Mechanism of action

NMImETIC NanoBone Plus is the first commercial synthetic osteoinductive product in the world in which two mineral and organic phases are in nano-scale. Its organic and mineral phases mimic the structure of natural bone. It is a product, composed of NMImETIC Peptide Nanofibers D (Peptide vial), a synthetic anti-inflammatory, angiogenic, and osteogenic self-assembling peptide nanofibers, spherical nanoceramics (Green Glass Vial) and NMImETIC Swelling NanoBone Powder vial, acting as a scaffold. NMImETIC Swelling NanoBone Powder vial, compared to allografts of equal weight, exhibits a 17.56% increase in volume, and compared to Osteon as a synthetic bone product, it shows a 38.3% volume increase. This means that for an equal weight, patients require less of this bone product. As a result, it will have lower total costs for patients while providing significant bone regeneration benefits. The part of peptide vial is US PATENT US10485895B2. The product is free from surfactants and toxic agents, and since it is entirely synthetic, there is no risk of contamination from a biological source. When NMImETIC NanoBone Plus interacts with bone, it creates a three-dimensional scaffold that fills cracks and repairs defects. Upon contact with bone, it activates the bone surface, leading to exposure of bone biomolecules on the bone surface, stimulating angiogenesis and strong bone regeneration. It significantly reduces the toothless time of dental implant patients compared to Allograft and Xenograft products.

Application

NMImETIC NanoBone Plus as a scaffold containing synthetic angiogenic, anti-inflammatory, and osteogenic self-assembling peptide nanofibers and nanoceramics enhance bone regeneration through the biological motifs of bone within self-assembling peptide nanofiber structure and spherical nanoceramics. The biocompatible and biodegradable bone scaffold accelerates bone healing. It is used in patients with damaged bones in areas lacking mechanical loading, such as craniofacial defects. The components within the NMImETIC Peptide Nanofiber D and mixed NanoBone are highly osteoinductive. For maximum bone regeneration, it’s recommended to use the entire Peptide Nanofiber and mixed NanoBone contents and then add swelled powder vial for mechanical and structural support.

Sinus Lift
Socket Preservation
Ridge Augmentation
Bone fracture healing
Craniofacial reconstruction
Spinal fusion surgeries
Filling bone voids and defects in orthopedic surgeries
Dental implant procedures for stabilizing artificial teeth
Enhancing bone support in joint replacement surgeries
Correcting bone deformities
Regenerating bone in periodontal treatments
Strengthening bone in spinal fusion procedure

Advantages

Osteoinductive
Being free from the risk of contamination from a biological source
Free from surfactants and toxic agents
Robust bone repair
Formation of nanofibers at the site
A greater volume compared to allografts and other synthetic materials of equal weight.
Usability in narrow spaces, effective coverage of uneven surfaces
Extra mechanical support and volume compared to the NMImETIC NanoBone
Biodegradable and Biocompatible (ISO 10993)