NMImETIC NanoBone Plus
Mechanism of action
NMImETIC NanoBone Plus is the first commercial synthetic osteoinductive product in the world in which two mineral and organic phases are in nano-scale. Its organic and mineral phases mimic the structure of natural bone. It is a product, composed of NMImETIC Peptide Nanofibers D (Peptide vial), a synthetic anti-inflammatory, angiogenic, and osteogenic self-assembling peptide nanofibers, spherical nanoceramics (Green Glass Vial) and NMImETIC NanoBone Powder vial, acting as a scaffold. The part of peptide vial is US PATENT US10485895B2. The product is free from surfactants and toxic agents, and since it is entirely synthetic, there is no risk of contamination from a biological source. When NMImETIC NanoBone Plus interacts with bone, it creates a three-dimensional scaffold that fills cracks and repairs defects. Upon contact with bone, it activates the bone surface, leading to exposure of bone biomolecules on the bone surface, stimulating angiogenesis and strong bone regeneration. It significantly reduces the toothless time of dental implant patients compared to Allograft and Xenograft products.
Accelerate your bone healing journey with NMImETIC NanoBone. Its innovative formula promotes enhanced bone growth, achieving 100% bone regeneration in a mere 2.5 months. This surpasses the performance of leading alternatives like NMImETIC Swelling NanoBone Powder (TBMT, Iran; 63.49%), Osteon II (Genoss, South Korea; 40.97%), NanoBone (Artoss, Germany; 36.20%), and Allograft (Iran; 24.59%), making it the ideal choice for faster and more effective bone healing.
Application
NMImETIC NanoBone Plus as a scaffold containing synthetic angiogenic, anti-inflammatory, and osteogenic self-assembling peptide nanofibers and nanoceramics enhance bone regeneration through the biological motifs of bone within self-assembling peptide nanofiber structure and spherical nanoceramics. The biocompatible and biodegradable bone scaffold accelerates bone healing. It is used in patients with damaged bones in areas lacking mechanical loading, such as craniofacial defects. The components within the NMImETIC Peptide Nanofiber D and mixed NanoBone are highly osteoinductive. For maximum bone regeneration, it’s recommended to use the entire Peptide Nanofiber and mixed NanoBone contents and then add swelled powder vial for mechanical and structural support.
- Sinus Lift
- Socket Preservation
- Ridge Augmentation
- Bone fracture healing
- Craniofacial reconstruction
- Spinal fusion surgeries
- Filling bone voids and defects in orthopedic surgeries
- Dental implant procedures for stabilizing artificial teeth
- Enhancing bone support in joint replacement surgeries
- Correcting bone deformities
- Regenerating bone in periodontal treatments
- Strengthening bone in spinal fusion procedure
Advantages
- Osteoinductive
- Being free from the risk of contamination from a biological source
- Free from surfactants and toxic agents
- Robust bone repair
- Formation of nanofibers at the site
- Usability in narrow spaces, effective coverage of uneven surfaces
- Extra mechanical support and volume compared to the NMImETIC NanoBone
- Biodegradable and Biocompatible (ISO 10993)
Ingredients
NMImETIC Peptide Nanofibers D
- Self-assembling peptide nanofibers and peptides 0.1%
- Pyrogen free distilled water 99.9%
NMImETIC Swelling NanoBone Powder (Powder and Granules)
Volume (ml)
- 0.5
- 1
- 1.5
- 2
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