NMImEIC Peptide Nanofibers

Mechanism of action

NMImETIC Peptide Nanofibers is a US PATENT US10485895B2 product, composed of  synthetic anti-inflammatory, angiogenic, and osteogenic self-assembling peptide nanofibers, acting as a scaffold. It is free from surfactants and toxic agents, and since it is entirely synthetic, there is no risk of contamination from a biological source.  It is sold in two models of Peptide Nanofibers (0.5 w/v) and Peptide Nanofibers D (Diluted 0.1 w/v). Its organic phase mimics the nanofiberous structure of natural bone. When NMImETIC Peptide Nanofibers interacts with bone, it creates a three-dimensional scaffold that fills cracks and repairs defects. Upon contact with bone, it activates the bone surface, leading to exposure of bone biomolecules on the bone surface, stimulating angiogenesis and strong bone regeneration.  It is biocompatible based on ISO 10993 standards and also, is biodegradable during one month and degraded to pure amino acids without toxic ingredients. In cases where the mechanical strength of the product is also required, and on the other hand, the patient is in a situation where the possibility of lower bone repair is low due to angiogenesis (Smokers, elderly patients and etc.), to increase the osteogenesis and angiogenesis potential of ceramics and allografts, adding NMImETIC Peptide Nanofibers is recommended.

Application

The application of NMImETIC Peptide Nanofibers as a scaffold with synthetic angiogenic, anti-inflammatory, and osteogenic properties enhances bone regeneration through the biological motifs of bone within its self-assembling peptide nanofiber structure. The biocompatible and biodegradable bone scaffold is utilized to promote bone healing. It is used in patients with damaged bones in areas lacking mechanical loading, such as craniofacial defects. It can be combined with other biomaterials such as allografts and ceramics to enhance allograft, xenograft or alloplastic osteogenic and angiogenic potentials.

• Ilizarov surgery
• Socket Preservation
• Ridge Augmentation
• Dental implant
• Craniofacial reconstruction
• Osteotomy
• Bone fracture healing
• Spinal fusion surgeries
• Filling bone voids and defects in orthopedic surgeries
• Dental implant procedures for stabilizing artificial teeth
• Enhancing bone support in joint replacement surgeries
• Correcting bone deformities
• Regenerating bone in periodontal treatments
• Strengthening bone in spinal fusion procedure

Advantages

Ingredients

NMImETIC Peptide Nanofibers 

• Self-assembling peptide nanofibers and peptides      0.5%
• Pyrogen free distilled water                                           99.5%

NMImETIC Peptide Nanofibers D

• Self-assembling peptide nanofibers and peptides      0.1%
• Pyrogen free distilled water                                           99.9%

Volume (ml)

• 0.25
• 0.5
• 1
• 1.5